Hyperglycemia

Whether hyperglycemia directly drives worse COVID-19 outcomes or merely marks underlying metabolic dysregulation is not yet established. Elevated glucose is confirmed to impair neutrophil function and innate immune response in bacterial in…

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Whether hyperglycemia directly drives worse COVID-19 outcomes or merely marks underlying metabolic dysregulation is not yet established. Elevated glucose is confirmed to impair neutrophil function and innate immune response in bacterial infections; extension of this mechanism to SARS-CoV-2 is plausible but unconfirmed. Patients with elevated blood glucose at presentation, including those without a diabetes diagnosis, demonstrate worse COVID-19 outcomes.