Hypothalamic-Pituitary-Ovarian Axis
The hormonal loop operates like a thermostat, with continuous negative feedback that turns hormone production up or down at thresholds. FSH and LH released by the pituitary travel to the ovaries and instruct them to produce estrogen and pr…
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The hormonal loop operates like a thermostat, with continuous negative feedback that turns hormone production up or down at thresholds. FSH and LH released by the pituitary travel to the ovaries and instruct them to produce estrogen and progesterone. The hypothalamus, as the master controller of the endocrine system, sends GnRH to signal the pituitary gland. Malfunction of the hormonal circuit from aging, stress, diet, or perimenopause produces estrogen imbalance.