ICU Admission

Survival associations with time from deterioration to intervention support ICU admission when organ injury first appears rather than after advanced organ failure. Earlier ICU transfer after deterioration may reduce intubation, septic shock, and mortality in patients with organ injury. Feasibility is measured by the proportion of intervention-arm patients with NEWS scores of 7 or higher who are admitted to ICU. Early ICU admission may increase ICU bed use and healthcare costs, making feasibility and cost-effectiveness important endpoints. In intervention centres, NEWS scores of 7 or higher trigger ICU admission within 3 hours.