Immune Modulation

Propolis provides systemic immune support relevant to colds, flu, upper respiratory infections, allergies, sinus issues, and fevers. Colostrum down-regulates overactive immune responses, making it useful for asthma and respiratory allergies where the immune system reacts excessively to benign triggers. A single four-spray application of about 100 mg glutathione is claimed to significantly increase IL-12, TNF-alpha, and interferon-gamma. Spermidine may theoretically improve vaccine efficacy by helping the immune system respond more appropriately, though this has not been confirmed clinically. The article contrasts the proposed immune effect of glutathione with corticosteroids such as prednisone, which can suppress immune activity. Naturally induced interferon is presented as potentially equivalent to exogenous interferon injections for achieving clinical benefits. The article states uncertainty about whether cytokine-related effects are direct or indirect through immune function. The immune-related mechanism is presented as a hypothesis rather than a settled conclusion. The immune markers discussed include IL-12, TNF-alpha, and interferon-gamma. Propolis research spans both in vitr…