Inheritance Patterns
No autosomal recessive gene was identified as the sole cause of any tumour in the cohort. The study argues that dominant germline variants were the operative mechanism for tumour development in this cohort. Cancer-predisposition genes impl…
1 sources - 3 claims
No autosomal recessive gene was identified as the sole cause of any tumour in the cohort. The study argues that dominant germline variants were the operative mechanism for tumour development in this cohort. Cancer-predisposition genes implicated in tumour cases included autosomal dominant, autosomal recessive, dual AD/AR, and unclassified inheritance patterns.