Inositol

Myo-inositol reduces hyperandrogenism, lowers elevated cholesterol, and improves ovarian insulin sensitivity. Inositol has a visual appearance similar to real cocaine. D-chiro-inositol specifically sensitizes insulin receptors in the most severe PCOS phenotypes and facilitates renal excretion of excess circulating glucose. Heavy use of inositol during Wolf of Wall Street production is described as causing Jonah Hill to be hospitalized for a vitamin D overdose. Inositol is used on film sets as a substitute for cocaine. Combining both inositol isomers hedges therapeutic efficacy by addressing both ovarian function and receptor-level insulin insensitivity. Inositol is the putative treatment for PCOS, with two isomers working in combination.