Intensive Weight Loss Intervention

The induction phase aims for at least 1% weight loss per week using nutritionally complete TDR products providing 800–850 kcal/day. Physical activity targets increase to 150–300 minutes of moderate activity per week plus two strength sessions weekly. Weight loss medication may be any nationally approved adult weight loss medication, but only one type is permitted at a time. During continuation, TDR products are reduced while a low-energy food-based Mediterranean or Nordic dietary pattern is introduced. The IWL programme targets at least 20% weight loss from baseline or a final BMI below 25 kg/m² over two years.