Intersubject Correlation

In simulations with signal present, BNR improved activation prediction over ISC while keeping false-positive rates low. ISC behaved better than BNR in the exact zero-signal simulation setting. ISC tests shared time-locked activity by corre…

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In simulations with signal present, BNR improved activation prediction over ISC while keeping false-positive rates low. ISC behaved better than BNR in the exact zero-signal simulation setting. ISC tests shared time-locked activity by correlating participant voxelwise time series. ISC is limited because it summarizes raw fMRI data heavily and does not directly estimate a latent shared neural response function. Intersubject correlation is the standard data-driven method for naturalistic fMRI.