Ischemic Stroke

Despite weak discrimination, tortuosity intervention produced a monotonic stroke-probability response in the strict subset. In the stroke cohort, nine of twenty Bézier features were statistically significant and six aligned with prior cali…

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Despite weak discrimination, tortuosity intervention produced a monotonic stroke-probability response in the strict subset. In the stroke cohort, nine of twenty Bézier features were statistically significant and six aligned with prior caliber-narrowing and fractal-dimension findings. Capping the model at two recurrent strokes was described as conservative because additional OAC-preventable events were not captured. The model simulated recurrent ischemic and hemorrhagic strokes, bleeding events, atrial fibrillation detection, and death in three-month cycles. Patients in the model could experience up to two recurrent strokes, with disability represented in separate poststroke health states. The stroke discrimination task was weak because its label combined past, concurrent, and post-imaging stroke. The mixed temporal stroke label limits interpretation of stroke results. Large-artery atherosclerotic disease and small-vessel occlusive disease account for about 40% of all ischemic strokes.