IV NAD Infusions

Restoring salvage pathway function before an infusion is more effective than taking betaine to manage side effects, because it enables repeated recycling of infused NAD. Individuals with functioning salvage pathways may tolerate the same IV NAD dose in approximately one hour rather than three. In aging cells with deficient NAMPT, IV NAD is only used once before being methylated and excreted, providing only a single pass of benefit. A 1-gram IV NAD infusion typically takes three hours and causes side effects including chest pressure, flushing, and nausea.