Lassa Fever

There are no approved vaccines for Lassa fever, although an rVSV-LASV-GPC vaccine has shown promising early results. Lassa fever is an acute febrile illness caused by Lassa virus that can progress to severe disease with substantial mortality. Lassa fever transmission mainly occurs from the rodent reservoir Mastomys natalensis, while human-to-human transmission most often occurs in healthcare settings. Nigeria carries the highest Lassa fever burden in West Africa, especially in Edo and Ondo states.