Lavender

Oral lavender at 160 mg (Silexan) outperformed lorazepam at 0.5 mg and paroxetine at 20 mg on the Hamilton Anxiety Scale. A 2019 network meta-analysis across five studies and 524 participants supports lavender essential oil's efficacy for…

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Oral lavender at 160 mg (Silexan) outperformed lorazepam at 0.5 mg and paroxetine at 20 mg on the Hamilton Anxiety Scale. A 2019 network meta-analysis across five studies and 524 participants supports lavender essential oil's efficacy for anxiety. Lavender's anxiolytic mechanism operates through serotonin and GABA modulation. Sesquiterpene compounds in lavender cross the blood-brain barrier, enabling central rather than only peripheral effects. Silexan is a proprietary oral lavender preparation standardized to linalool acetate and linalool, licensed as a pharmaceutical in Germany.