Left Dorsolateral Prefrontal Cortex

The trial favors DLPFC targeting over canonical language areas because the DLPFC is less affected by neurodegeneration in PPA. The DLPFC supports cognitive functions that can enhance language performance. The lateral prefrontal cortex is d…

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The trial favors DLPFC targeting over canonical language areas because the DLPFC is less affected by neurodegeneration in PPA. The DLPFC supports cognitive functions that can enhance language performance. The lateral prefrontal cortex is described as an integrative hub for language-related circuits because of its connectivity with frontoparietal and attention networks. The left DLPFC is the stimulation target for all PPA variants in the trial.