Letrozole

Letrozole may preserve endometrial receptivity, making it potentially superior to clomiphene for implantation outcomes. Prior systematic reviews have addressed the letrozole versus clomiphene contrast but cannot provide simultaneous rankin…

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Letrozole may preserve endometrial receptivity, making it potentially superior to clomiphene for implantation outcomes. Prior systematic reviews have addressed the letrozole versus clomiphene contrast but cannot provide simultaneous ranking across all treatment strategies. Letrozole is an aromatase inhibitor that suppresses oestrogen synthesis centrally, triggering FSH release without the peripheral anti-oestrogenic effects seen with clomiphene.