Low-Dose-Rate Brachytherapy
LDR brachytherapy delivers continuous local radiation from a single implant, unlike high-dose-rate brachytherapy delivered through temporary catheters. The LDR brachytherapy prescription dose target is 145 Gy. Iodine-125 in LDR brachythera…
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LDR brachytherapy delivers continuous local radiation from a single implant, unlike high-dose-rate brachytherapy delivered through temporary catheters. The LDR brachytherapy prescription dose target is 145 Gy. Iodine-125 in LDR brachytherapy has a 60-day half-life, so radiation dose accumulates gradually over months. For the LDR arm, preoperative TRUS measurements are used by a web-based nomogram to calculate seed requirements. LDR brachytherapy is a day-case interventional radiotherapy procedure involving permanent implantation of radioactive iodine-125 seeds into the prostate.