Macrophage M0

The strongest validated signal was the M0 macrophage signature using the pan-cancer CIBERSORTx matrix and ensemble classifier. Predicted M0-high patients had longer overall survival than predicted M0-low patients in the study’s survival an…

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The strongest validated signal was the M0 macrophage signature using the pan-cancer CIBERSORTx matrix and ensemble classifier. Predicted M0-high patients had longer overall survival than predicted M0-low patients in the study’s survival analysis. The M0 signature depended on distributed imaging features rather than a single dominant measurement. MRI appears to contain a radiomic phenotype associated with M0 macrophage abundance or status in the glioblastoma immune microenvironment.