Maternal Glycemia
Current clinical standards classify maternal glycemia too coarsely to capture the full spectrum of glycemic exposure. The primary exposure is a composite OGTT sum of glucose z-scores from a fasting 3-hour 100 g oral glucose tolerance test…
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Current clinical standards classify maternal glycemia too coarsely to capture the full spectrum of glycemic exposure. The primary exposure is a composite OGTT sum of glucose z-scores from a fasting 3-hour 100 g oral glucose tolerance test at 24-28 weeks gestation. The OGTT composite captures the full glycemic excursion profile by integrating fasting and post-load glucose values. Continuous glucose monitoring is used at two pregnancy windows to capture glycemic variability that a single OGTT cannot capture.