Matrix Gla Protein

There are over 3,500 published research papers on Vitamin K2's role in directing calcium away from soft tissue. Matrix Gla Protein (MGP) is a K2-dependent protein that actively inhibits calcium deposition inside arterial walls. MGP is enti…

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There are over 3,500 published research papers on Vitamin K2's role in directing calcium away from soft tissue. Matrix Gla Protein (MGP) is a K2-dependent protein that actively inhibits calcium deposition inside arterial walls. MGP is entirely dependent on Vitamin K2 for activation and cannot function without it. Matrix Gla Protein keeps calcium bound to bone rather than allowing it to deposit in soft tissue. When K2 is insufficient, MGP remains inactive and cannot clear calcium from arteries, leading to progressive vascular calcification.