Mechanisms of Harm

Toxic metals can accumulate in mitochondria and reduce ATP output. Toxic metals interfere with enzymes, protein synthesis, and nutrient absorption. Multiple toxic metals are presented as having synergistic rather than merely additive toxic…

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Toxic metals can accumulate in mitochondria and reduce ATP output. Toxic metals interfere with enzymes, protein synthesis, and nutrient absorption. Multiple toxic metals are presented as having synergistic rather than merely additive toxicity. Toxic metal accumulation increases reactive oxygen species production, especially from lead and cadmium. Excess reactive oxygen species can damage cell membranes and generate lipid oxidation products.