Melanocyte Stem Cells
Stress-induced graying is characterized by acute exhaustion of the melanocyte stem cell reservoir. When all melanocyte stem cells are mobilized and matured simultaneously, the follicle's reserve pool is entirely depleted in a very short pe…
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Stress-induced graying is characterized by acute exhaustion of the melanocyte stem cell reservoir. When all melanocyte stem cells are mobilized and matured simultaneously, the follicle's reserve pool is entirely depleted in a very short period. Under severe stress, a neuroendocrine signal causes melanocyte stem cells to rapidly and prematurely mature into fully differentiated melanocytes.