Metabolomics

Metabolomics can identify dysfunction before any diagnosable disease has emerged, enabling early intervention. Metabolomics can reveal co-factor deficiencies and cellular energy pathway inefficiencies before any symptoms appear. Unlike standard lab tests that measure individual markers in isolation, metabolomics reveals the flow of biochemistry including where pathways are blocked or deficient. Metabolomics tracks individuals against their own baseline rather than against population averages. Metabolomics can detect overtraining, mitochondrial depletion, or fueling deficiencies that standard lab panels miss. Metabolomics can detect predictive signals for disease decades before they appear in standard blood tests. Standard cardiovascular risk assessment focuses on LDL while missing the broader metabolic picture. The preferred mitochondrial assessment is a functional VO2-based test measuring oxygen use and carbon dioxide production. Retrospective metabolomic validation uses archived dried bloodspots to distinguish normal from abnormal bloodspot profiles. Blood tests and isolated cell tests are described as inadequate for assessing whole-body mitochondrial performance. The metabolomi…