Mitochondrial DNA Inheritance

Rare paternal mitochondrial inheritance does not overturn maternal inheritance as the primary rule. Rare documented cases show that paternal mitochondrial DNA inheritance can occur. An investigation across three unrelated families identifi…

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Rare paternal mitochondrial inheritance does not overturn maternal inheritance as the primary rule. Rare documented cases show that paternal mitochondrial DNA inheritance can occur. An investigation across three unrelated families identified 17 people with paternal mitochondrial contribution. Mitochondrial DNA is generally inherited from the mother because sperm mitochondria are usually destroyed during fertilization.