Mitochondrial Dysfunction

Mitochondrial dysfunction is associated with several psychiatric and neurodegenerative disorders. The article states that other programs will not work until cellular energy production is restored. The article says compromised cellular energy production prevents mitochondria from supporting adrenal function, detoxification, or other programs. Mitochondria require nutrients to maintain ATP production and oxidative-stress regulation. Nutrient depletion is said to produce elevated homocysteine, oxidative stress, and decreased membrane lipids. The article presents Dr. Chris Palmer's model as viewing mental disorders as metabolic brain disorders rooted in mitochondrial dysfunction. Specific nutrients support mitochondria and neurotransmitter systems against cortisol- and glutamate-related damage. Severe mitochondrial dysfunction must be treated first and as a standalone intervention. Severe mitochondrial dysfunction is described as the only clear scenario requiring standalone-first treatment.