MOI-A Study
Participants are randomised equally to target losartan doses of 25 mg, 50 mg, or 75 mg once daily. The trial aims to identify the Optimal Biologic Dose of losartan for adolescents and adults with osteogenesis imperfecta to inform a later p…
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Participants are randomised equally to target losartan doses of 25 mg, 50 mg, or 75 mg once daily. The trial aims to identify the Optimal Biologic Dose of losartan for adolescents and adults with osteogenesis imperfecta to inform a later phase III trial.