mRNA Medicine

COVID-era mRNA vaccines demonstrated programmable medicine at global scale. mRNA temporarily instructs cells to make a protein and does not rewrite the genome. Lipid nanoparticles protect fragile RNA and help deliver it into cells. Early l…

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COVID-era mRNA vaccines demonstrated programmable medicine at global scale. mRNA temporarily instructs cells to make a protein and does not rewrite the genome. Lipid nanoparticles protect fragile RNA and help deliver it into cells. Early lipid nanoparticle delivery is limited because it is relatively nonspecific across cell types. mRNA is a programmable tool that can be designed to produce many different proteins.