Multi-Omic Analysis

RNA is treated as more informative than DNA for current health state because it reflects active gene expression. Transcriptomics means measuring RNA transcripts. Circulating PBMC analyses combine bulk RNA sequencing and comprehensive proteomics to identify molecular signatures of progression. The test analyzes microbial and human transcripts across the oral cavity, gut, blood, epithelial cells, and mitochondria. Pathway enrichment and multi-omic network integration will identify biologically relevant processes and upstream regulatory factors. AI is described as mapping transcripts to biological functions, biomarker states, and personalized recommendations. The full testing model uses saliva, finger-prick blood, and a small fecal sample. Single-cell RNA sequencing from a subset of samples will refine implicated immune cell populations.