Multinational Validation Study

The cluster randomized trial will compare HAPI incidence and the effectiveness and cost-effectiveness of IDEAL SKIIN CARES delivered by trained wound specialist nurses versus routine care. Geographic diversity was central to assessing how well risk prediction tools perform across different populations and healthcare contexts. Geographic diversity was central to the validation approach, enabling assessment of risk tool performance across different populations and healthcare contexts. The study involved 56 co-investigators from academic institutions, research centers, and health systems spanning 11 countries. The study involved 56 co-investigators from institutions across 11 countries including Australia, UK, USA, Japan, and Singapore. This study is described as a large-scale multinational validation of cardiovascular risk equations. The research involved 56 co-investigators from institutions across 11 countries including Australia, UK, USA, France, Sweden, Netherlands, Spain, Germany, Canada, Japan, and Singapore. Geographic diversity was a central design element of the validation approach. The study enrolled a cohort of 6.4 million individuals to validate the two cardiovascular ri…