Neurogenesis
Psilocybin upregulates BDNF and shows clinical efficacy for depression, anxiety, and PTSD. Ibogaine treatment has produced measurable increases in brain volume in veterans with TBI and PTSD, representing a potential reversal of brain atrop…
2 sources - 11 claims
Psilocybin upregulates BDNF and shows clinical efficacy for depression, anxiety, and PTSD. Ibogaine treatment has produced measurable increases in brain volume in veterans with TBI and PTSD, representing a potential reversal of brain atrophy. The brain continuously regenerates neurons, and the rate of regeneration directly determines cognitive function with age. The brain consumes 20% of the body's total oxygen and metabolic output despite making up only 2% of body weight. BDNF is a key signal in neurogenesis and is sometimes described as 'miracle-grow for the brain.' Most neurogenesis research focuses on the hippocampus, a region involved in memory, spatial navigation, and problem solving. The adult brain retains neurogenic capacity throughout life, contradicting the classical teaching that lost neurons cannot be replaced. Memory lapses may result from poor diet or unstable blood sugar rather than neurodegeneration. Beta-D-glucan in culinary mushrooms and barley stimulates angiogenesis, which indirectly promotes neurogenesis because nerves require blood vessel support to grow. Repeatedly drawing attention to someone's memory errors can worsen the problem by reinforcing those mist…