Neuropeptide-Y
Neuropeptide-Y has strong proarrhythmic effects that persist even during maximal beta-blockade. The proarrhythmic effects of neuropeptide-Y are mediated through ventricular myocyte Y1 receptor promotion of calcium signalling. Neuropeptide-…
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Neuropeptide-Y has strong proarrhythmic effects that persist even during maximal beta-blockade. The proarrhythmic effects of neuropeptide-Y are mediated through ventricular myocyte Y1 receptor promotion of calcium signalling. Neuropeptide-Y may act as a biomarker of arrhythmic risk and predicts arrhythmia and death in chronic heart failure and after myocardial infarction.