Non-Pharmacological Fatigue Interventions

Eligible interventions required randomized trial evidence with long-term fatigue outcomes beyond three months after treatment ended. Eligible interventions had to show a statistically significant difference versus usual care in the network meta-analysis at short-term or long-term follow-up. Remote ischaemic conditioning was excluded because its evidence came from a single stroke study and was unlikely to generalise. The model evaluated physical activity promotion, CBT-Fatigue, and mindfulness as eligible intervention categories. Interventions had to be generalisable across chronic conditions to be included in the economic model.