OCD Brain Circuits

OCD, eating disorders, addiction, and some impulsive states share pursuit of urges despite risk. OCD involves abnormal activity across cortical and subcortical brain regions. The ventral striatum and nucleus accumbens are central to a mode…

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OCD, eating disorders, addiction, and some impulsive states share pursuit of urges despite risk. OCD involves abnormal activity across cortical and subcortical brain regions. The ventral striatum and nucleus accumbens are central to a model of compulsive behavior. Perturbation of the ventral striatum may support compulsive pursuit of reward or relief despite punishment or risk.