Onchocerciasis-Associated Epilepsy
Successful onchocerciasis elimination programmes are associated with reduced OAE prevalence. The causal mechanism linking onchocerciasis to epilepsy has not been established. Proposed pathogenic mechanisms of OAE include direct CNS invasio…
1 sources - 7 claims
Successful onchocerciasis elimination programmes are associated with reduced OAE prevalence. The causal mechanism linking onchocerciasis to epilepsy has not been established. Proposed pathogenic mechanisms of OAE include direct CNS invasion by microfilariae, passage of excretory-secretory products across the blood-brain barrier, Wolbachia involvement, and immune-triggered neurological injury.