Pneumococcal Conjugate Vaccine

The largest reported single protective PCV effect was against influenza hospitalisation in fully vaccinated Spanish children during the pandemic wave. Most PCV studies reported beneficial or neutral effects. Six studies examined PCV agains…

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The largest reported single protective PCV effect was against influenza hospitalisation in fully vaccinated Spanish children during the pandemic wave. Most PCV studies reported beneficial or neutral effects. Six studies examined PCV against laboratory-confirmed viral or bacterial hospitalisations. PCV was included only for pathogen-confirmed outcomes to reduce confounding from non-specific clinical diagnoses. Some negative PCV associations were observed for adenovirus-confirmed hospitalisations in children older than 12 months.