Post-COVID Immune Debt

The post-pandemic surge of severe childhood illness was the immune system functioning as designed, not a failure. Antibodies disappear within 8 weeks to 6 months after infection or vaccination if there is no re-exposure, after which the im…

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The post-pandemic surge of severe childhood illness was the immune system functioning as designed, not a failure. Antibodies disappear within 8 weeks to 6 months after infection or vaccination if there is no re-exposure, after which the immune system shifts to a memory phase. Two years of pandemic social isolation erased the antibody protection children had built through ordinary childhood transmission.