Preconception TSH
The TSH–birth weight relationship is age-dependent and does not generalise to women aged 25–39. The TSH level associated with the lowest odds ratio for LGA was 1.62 mIU/L in the 20–24 age group. No statistically significant association bet…
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The TSH–birth weight relationship is age-dependent and does not generalise to women aged 25–39. The TSH level associated with the lowest odds ratio for LGA was 1.62 mIU/L in the 20–24 age group. No statistically significant association between preconception TSH and LGA, SGA, or AGA was found in women aged 25–39 across all TSH ranges tested. A significant non-linear (U-shaped) association between preconception TSH and both LGA and AGA was identified exclusively in women aged 20–24 years. Both low and high preconception TSH were associated with significantly increased LGA risk and reduced AGA likelihood compared to the reference range. Maternal TSH serves as an accessible proxy for thyroid function and its downstream effects on fetal growth.