Preoperative Opioid Use

Patients awaiting THA or TKA often use opioid analgesics for chronic pain despite limited evidence of benefit and known harms. Preoperative opioid use is described as the strongest predictor of persistent opioid use after surgery. Regular…

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Patients awaiting THA or TKA often use opioid analgesics for chronic pain despite limited evidence of benefit and known harms. Preoperative opioid use is described as the strongest predictor of persistent opioid use after surgery. Regular preoperative opioid use increases in-hospital opioid-related adverse drug events, including constipation and respiratory depression.