Probiotic Formulation

Preclinical work found that using the probiotic strains alone, without their prebiotic substrates, produced inferior efficacy. One strain in the formulation may produce GABA, a neurotransmitter, which could explain sleep disruption reported by some evening users. The Pendulum product combines probiotic microbial strains and the prebiotic fibers that feed them within the same capsule. The capsule is enteric coated to survive stomach acidity and deliver microbes to the colon, and taking it with food is recommended because food reduces stomach acidity. Customers who switched from evening to morning-only dosing reportedly resolved sleep problems and experienced reduced post-lunch energy crashes.