Procedural Sedation and Analgesia

The prior ERCP comparative study targeted lighter sedation (MOAA/S score of 1–2) rather than the deep sedation (MOAA/S score of 0) targeted in the present trial. PSA requires preservation of airway patency, spontaneous respiration, protect…

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The prior ERCP comparative study targeted lighter sedation (MOAA/S score of 1–2) rather than the deep sedation (MOAA/S score of 0) targeted in the present trial. PSA requires preservation of airway patency, spontaneous respiration, protective airway reflexes, and haemodynamic stability. Deep sedation in elderly patients carries a substantially elevated risk of respiratory depression compared with younger adults. Procedural sedation and analgesia is defined as the administration of one or more pharmacological agents to reduce patient anxiety and discomfort during diagnostic and therapeutic procedures while preserving key physiological functions.