Pulmonary Function

Greater chest expansion independently predicted higher VO2max and protected against low physical activity. In typical adults, adequate lecithin supports optimal oxygen exchange at the alveolar level. AS patients had worse pulmonary function and reduced chest expansion compared with controls. Pulmonary function was assessed with calibrated spirometry following ATS and ERS procedures. FVC, FEV1, and FEV1/FVC ratio were recorded as predicted values adjusted for demographic and anthropometric factors. Pulmonary surfactant, which prevents alveolar collapse, is primarily composed of phosphatidylcholine, a form of lecithin. The lungs take in oxygen and release carbon dioxide. Costovertebral joint ankylosis and chest wall restriction may reduce chest expansion and contribute to lower spirometry values. Genetic conditions causing insufficient lecithin production result in severe respiratory problems from birth.