Quality-of-Life Risk Factors

Age was significantly associated with lower quality of life in both complete case and imputed analyses. No longer working was another significant factor associated with lower quality of life. A family history of pain was significantly associated with reduced quality of life. Gender was not a statistically significant factor in reduced quality of life after adjustment. Quality-of-life scores declined with age across groups. Comorbidities were more common among REMS-positive participants but did not show a statistically significant independent impact on quality of life in the model.