Regional Citrate Anticoagulation
RCA is particularly important for patients with high haemorrhage risk. Citrate prevents extracorporeal circuit thrombosis by chelating ionised calcium into soluble calcium-citrate complexes. Lower circuit ionised calcium inhibits the coagu…
1 sources - 5 claims
RCA is particularly important for patients with high haemorrhage risk. Citrate prevents extracorporeal circuit thrombosis by chelating ionised calcium into soluble calcium-citrate complexes. Lower circuit ionised calcium inhibits the coagulation cascade. Systemic coagulation is restored after blood returns to the patient through calcium supplementation. RCA is described as the preferred anticoagulation strategy for CRRT.