Sample Size and Power

The trial plans 20 active hospitals and a total sample size of 20,000 patients. The internal pilot classifies green status as an average of 200 patients per hospital, amber as 150 to 199 patients, and red as fewer than 150 patients. The trial has 89.5% power to detect a reduction in 90-day readmission from 16.7% to 13.7%. About 10% of patients or consultees are expected to consent to additional patient-reported outcome data, based on the feasibility study. The internal pilot uses Step 1 hospitals and enrolment over three months.