SASP
SASP consists of factors secreted by senescent cells, including inflammatory molecules and growth factors. SASP may make nearby cells more likely to become senescent. Secondary senescence is described as neighboring cells becoming senescen…
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SASP consists of factors secreted by senescent cells, including inflammatory molecules and growth factors. SASP may make nearby cells more likely to become senescent. Secondary senescence is described as neighboring cells becoming senescent because of senescent-cell secretions. Senescent-cell burden may increase nonlinearly as SASP factors promote additional senescence.