Segmental Duplications
A pair of segmental duplications is expected to stop being recognizable as matching duplications after roughly 40 million years under criteria from Jiang et al. Matching segmental duplications are proposed as a plausible biological correla…
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A pair of segmental duplications is expected to stop being recognizable as matching duplications after roughly 40 million years under criteria from Jiang et al. Matching segmental duplications are proposed as a plausible biological correlate of transient fragile regions. The sequence similarity of matching segmental duplications decays through mutation. The decay of segmental-duplication similarity provides a possible mechanism for fragile sites having limited active periods. Newly duplicated matching regions may promote rearrangement.