Self-Controlled Risk Interval Design
Because each person serves as their own control, the design controls for known and unknown confounders that are stable over time. Only vaccinated people who experience an outcome during prespecified risk or control intervals contribute to…
1 sources - 5 claims
Because each person serves as their own control, the design controls for known and unknown confounders that are stable over time. Only vaccinated people who experience an outcome during prespecified risk or control intervals contribute to the inferential analysis. The design is suitable for transient exposures such as vaccination and acute outcomes such as GBS, ADEM, and AF.