Serotonin Pathway
The article recommends 5-HTP with B6 in the evening for low 5-HIAA, while noting not all patients tolerate 5-HTP. Antidepressants or 5-HTP before the test can artificially elevate 5-HIAA. Tryptophan is the dietary precursor for serotonin,…
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The article recommends 5-HTP with B6 in the evening for low 5-HIAA, while noting not all patients tolerate 5-HTP. Antidepressants or 5-HTP before the test can artificially elevate 5-HIAA. Tryptophan is the dietary precursor for serotonin, and serotonin is the precursor to melatonin. Drax's non-detectable 5-HIAA was interpreted as explaining insomnia through impaired serotonin production and inadequate melatonin substrate.