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SOFA, APACHE II, and CURB-65 outperformed oxygenation-based measures for mortality prediction but still had only poor-to-modest discrimination. CURB-65 performed comparably to APACHE II even though it was developed for community-acquired p…
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SOFA, APACHE II, and CURB-65 outperformed oxygenation-based measures for mortality prediction but still had only poor-to-modest discrimination. CURB-65 performed comparably to APACHE II even though it was developed for community-acquired pneumonia rather than ARDS. Higher Berlin, SOFA, APACHE II, and CURB-65 scores were independently associated with increased mortality risk. CURB-65 showed the largest adjusted association with mortality despite weaker discrimination than APACHE II and SOFA in the multi-domain group.