Somatic Stem Cells
Lifetime cancer risk across tissues correlates with the total number of divisions of normal self-renewing somatic stem cells. More accurate counts of susceptible somatic stem cells would be needed for more exact parameter estimation. The t…
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Lifetime cancer risk across tissues correlates with the total number of divisions of normal self-renewing somatic stem cells. More accurate counts of susceptible somatic stem cells would be needed for more exact parameter estimation. The theory describes a per-somatic-stem-cell hazard rate rather than a direct tissue-level hazard. Pre-tumorigenic somatic stem cells may be detectable before they become tumorigenic.