Sources of Inflammation

Obesity can make fat tissue an active inflammatory organ because damaged fat tissue recruits immune cells that release cytokines. Leaky gut can allow microbial products into circulation, activating immune cells that release inflammatory molecules affecting the brain. Chronic inflammation can arise from obesity, stress, early trauma, dysbiosis, leaky gut, infections, medical treatments, and aging-related metabolic changes. Early stress and trauma can produce long-lasting changes in immune regulation that bias the body toward inflammation. Medical interventions such as surgery, radiation, chemotherapy, and cancer immune therapies can trigger inflammatory responses.