Staphylococcus aureus bacteraemia

S. aureus coagulation-linked enzymes promote fibrin deposition around bacterial clusters. S. aureus coagulation-dependent pathogenesis creates a potential target for an anticoagulant with direct anti-enzyme activity. SAB has high reported mortality at both 30 and 90 days. Staphylococcus aureus bacteremia is associated with high bacterial-related mortality in adults. Mortality after Staphylococcus aureus bacteraemia remains high at 20-30% within 90 days. Staphylococcus aureus bacteraemia is a severe bloodstream infection with poor outcomes despite active standard antibiotics. Staphylococcus aureus bacteraemia can spread to secondary body sites and relapse after treatment.